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Danusertib (PHA-739358), 5mg
1.331,61 RON
SKU
SKM_S1107_5mg
Danusertib (PHA-739358) is an Aurora kinaseinhibitor for Aurora A/B/Cwith IC50of 13 nM/79 nM/61 nM in cell-free assays, modestly potent to Abl, TrkA, c-RET and FGFR1, and less potent to Lck, VEGFR2/3, c-Kit, CDK2, etc. Danusertib induces apoptosis, cell cycle arrest, and autophagy. Phase 2.
| Price | 1.119,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
Danusertib (PHA-739358) is an Aurora kinaseinhibitor for Aurora A/B/Cwith IC50of 13 nM/79 nM/61 nM in cell-free assays, modestly potent to Abl, TrkA, c-RET and FGFR1, and less potent to Lck, VEGFR2/3, c-Kit, CDK2, etc. Danusertib induces apoptosis, cell cycle arrest, and autophagy. Phase 2. |
