Cu-CPT22, 25mg

Cu-CPT22, 25mg

BTK inhibitor 1 (Compound 27), 2mg

BTK inhibitor 1 (Compound 27), 2mg

Cu-CPT22, 10mM/1mL

1.501,78 RON
SKU
SKM_S8677_10mM/1mL

CU-CPT22 shows dose-dependent inhibitory effects blocking Pam3CSK4-induced TLR1/2activation with an IC50 of 0.58 ± 0.09 µM while no significant inhibition to TLR2/6. It demonstrates minimal non-specific inhibition against a panel of 10 representative kinases (PDGFRB, MET, DDR2, SRC, MAPK1, PAK1, AKT1, PKC-γ, CAMK1, and PLK4).

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Description

CU-CPT22 shows dose-dependent inhibitory effects blocking Pam3CSK4-induced TLR1/2activation with an IC50 of 0.58 ± 0.09 µM while no significant inhibition to TLR2/6. It demonstrates minimal non-specific inhibition against a panel of 10 representative kinases (PDGFRB, MET, DDR2, SRC, MAPK1, PAK1, AKT1, PKC-γ, CAMK1, and PLK4).