SB431542, 10mM/1mL

SB431542, 10mM/1mL

Crizotinib, 50mg

Crizotinib, 50mg

Crizotinib, 5mg

1.180,48 RON
SKU
SKM_S1068_5mg

Crizotinib is a potent inhibitor of c-Metand ALKwith IC50of 11 nM and 24 nM in cell-based assays, respectively. It is also a potent ROS1inhibitor with Ki value less than 0.025 nM. Crizotinib induces autophagythrough inhibition of the STAT3 pathway in multiple lung cancer cell lines.

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Description

Crizotinib is a potent inhibitor of c-Metand ALKwith IC50of 11 nM and 24 nM in cell-based assays, respectively. It is also a potent ROS1inhibitor with Ki value less than 0.025 nM. Crizotinib induces autophagythrough inhibition of the STAT3 pathway in multiple lung cancer cell lines.