Cinobufagin, 5mg

Cinobufagin, 5mg

Dehydroabietic acid, 1mg

Dehydroabietic acid, 1mg

Cinobufagin, 1mg

860,37 RON
SKU
SKM_S3224_1mg

Cinobufagin (Cinobufagine), an active ingredient of Venenum Bufonis, inhibits tumor development. Cinobufagin increases ATMand Chk2and decreases CDC25C, CDK1, and cyclin B. Cinobufagin inhibits PI3K, AKT and Bcl-2while increases levels of cleaved caspase-9and caspase-3. Thus, Cinobufagin induces cell cycle arrest at the G2/M phase and apoptosis.

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Description

Cinobufagin (Cinobufagine), an active ingredient of Venenum Bufonis, inhibits tumor development. Cinobufagin increases ATMand Chk2and decreases CDC25C, CDK1, and cyclin B. Cinobufagin inhibits PI3K, AKT and Bcl-2while increases levels of cleaved caspase-9and caspase-3. Thus, Cinobufagin induces cell cycle arrest at the G2/M phase and apoptosis.