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Chebulagic acid, 1mg

2.156,28 RON
SKU
SKM_E0226_1mg

Chebulagic acid, isolated form Terminalia chebula Retz, is a reversible and non-competitive inhibitor of maltasewith a Ki value of 6.6 μM. Chebulagic acid shows potent anti-inflammatoryeffects in LPS-stimulated RAW 264.7 cells. Chebulagic acid also shows potent COX-LOXdual inhibition activity with IC50 values of 15 μM, 0.92 μM and 2.1 μM for COX-1, COX-2 and 5-LOX respectively.

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Description

Chebulagic acid, isolated form Terminalia chebula Retz, is a reversible and non-competitive inhibitor of maltasewith a Ki value of 6.6 μM. Chebulagic acid shows potent anti-inflammatoryeffects in LPS-stimulated RAW 264.7 cells. Chebulagic acid also shows potent COX-LOXdual inhibition activity with IC50 values of 15 μM, 0.92 μM and 2.1 μM for COX-1, COX-2 and 5-LOX respectively.