GA-017, 10mM/1mL

GA-017, 10mM/1mL

CHD1Li 6.11, 25mg

CHD1Li 6.11, 25mg

CHD1Li 6.11, 5mg

2.208,64 RON
SKU
SKM_E1146_5mg

CHD1Li 6.11, a potent oncogenic chromodomain helicase DNA binding protein 1 like (CHD1L)inhibitor and an orally bioavailable antitumor agent, shows the enzymatic inhibition of the catalytic CHD1L (cat-CHD1L) recombinant proteinwith IC50 of 3.3 µM, and significantly reduces the tumor volume of colorectal cancer (CRC) xenografts generated from isolated quasi mesenchymal cells (M-Phenotype). 

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Description

CHD1Li 6.11, a potent oncogenic chromodomain helicase DNA binding protein 1 like (CHD1L)inhibitor and an orally bioavailable antitumor agent, shows the enzymatic inhibition of the catalytic CHD1L (cat-CHD1L) recombinant proteinwith IC50 of 3.3 µM, and significantly reduces the tumor volume of colorectal cancer (CRC) xenografts generated from isolated quasi mesenchymal cells (M-Phenotype).