4-Methylesculetin, 25mg

4-Methylesculetin, 25mg

Ceritinib dihydrochloride, 25mg

Ceritinib dihydrochloride, 25mg

Ceritinib dihydrochloride, 5mg

1.180,48 RON
SKU
SKM_S4967_5mg

Ceritinib (Zykadia, LDK378) dihydrochloride is a selective, orally bioavailable and ATP-competitive inhibitor of ALKwith IC50 of 0.2 nM. Ceritinib dihydrochloride also inhibits InsR, IGF-1Rand STK22Dwith IC50 of 7 nM, 8 nM and 23 nM, respectively. Ceritinib exhibits antitomor activity.

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Description

Ceritinib (Zykadia, LDK378) dihydrochloride is a selective, orally bioavailable and ATP-competitive inhibitor of ALKwith IC50 of 0.2 nM. Ceritinib dihydrochloride also inhibits InsR, IGF-1Rand STK22Dwith IC50 of 7 nM, 8 nM and 23 nM, respectively. Ceritinib exhibits antitomor activity.