Celastrol, 50mg

Celastrol, 50mg

Celastrol, 10mM/1mL

Celastrol, 10mM/1mL

Celastrol, 1g

13.034,07 RON
SKU
SKM_S1290_1g

Celastrol is a potent proteasomeinhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50of 2.5 μM. Celastrol induces apoptosisand autophagyvia the ROS/JNK signaling pathway. Celastrol inhibits dopaminergic neuronal death of Parkinson's disease through activating mitophagy.

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Description

Celastrol is a potent proteasomeinhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50of 2.5 μM. Celastrol induces apoptosisand autophagyvia the ROS/JNK signaling pathway. Celastrol inhibits dopaminergic neuronal death of Parkinson's disease through activating mitophagy.