Limba
Romanian
Romanian
English|
Cediranib (AZD2171, NSC-732208) is a highly potent VEGFR(KDR)inhibitor with IC50of <1 nM, also inhibits Flt1/4 with IC50of 5 nM/≤3 nM, similar activity against c-Kit and PDGFRβ, 36-, 110-fold and >1000-fold selective more for VEGFR than PDGFR-α, CSF-1R and Flt3 in HUVEC cells. Cediranib (AZD2171) induces autophagic vacuole accumulation. Phase 3.
| Price | 992,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
Cediranib (AZD2171, NSC-732208) is a highly potent VEGFR(KDR)inhibitor with IC50of <1 nM, also inhibits Flt1/4 with IC50of 5 nM/≤3 nM, similar activity against c-Kit and PDGFRβ, 36-, 110-fold and >1000-fold selective more for VEGFR than PDGFR-α, CSF-1R and Flt3 in HUVEC cells. Cediranib (AZD2171) induces autophagic vacuole accumulation. Phase 3. |
