Anti-Cytokeratin 19, mouse monoclonal, 1 ml, Species x-Reactivity: human, Applications: IHC

CK19

Cat#: BSH-7240-100 100ul, BSH-7240-1 1ml, BSH-7240-RTU 7ml
Clone: BS23
S/R: human, dog
Application: IHC
Tissue control: Liver, appendix, breast cancer

Cytokeratin 19, also known as KRT19, CK19, CK19, K1CS, MGC15366. Entrez Protein NP_002267. It is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis.

CK19 stained tissue sections. CK19 Optibody (Clone: BS23) shows similar and more intensity staining pattern as the optimal staining criteria and columnar epithelia of appendix is strongly stained without any background staining (a). CK19 shows breast lobular carcinoma cells as well as ductal breast carcinoma cells clearly (b). Only epithelia of bile ducts are stained in liver tissue section.