Limba
Romanian
Romanian
English|
Capmatinib is a novel, ATP-competitive inhibitor of c-METwith IC50of 0.13 nM in a cell-free assay, inactive against RONβ, as well as EGFR and HER-3. Capmatinib (INCB28060) inhibits Wnt/β-cateninand EMT signaling pathways and induces apoptosisin diffuse gastric cancer positive for c-MET amplification. Phase 1.
| Price | 8.142,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
Capmatinib is a novel, ATP-competitive inhibitor of c-METwith IC50of 0.13 nM in a cell-free assay, inactive against RONβ, as well as EGFR and HER-3. Capmatinib (INCB28060) inhibits Wnt/β-cateninand EMT signaling pathways and induces apoptosisin diffuse gastric cancer positive for c-MET amplification. Phase 1. |
