α-santonin, 25mg

α-santonin, 25mg

Cabozantinib malate, 50mg

Cabozantinib malate, 50mg

Cabozantinib malate, 10mg

1.180,48 RON
SKU
SKM_S4001_10mg

Cabozantinib malate (XL184) is the malate of Cabozantinib, a potent VEGFR2inhibitor with IC50of 0.035 nM and also inhibits c-Met, Ret (c-Ret), Kit (c-Kit), Flt-1/3/4, Tie2, and AXL with IC50of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively. Cabozantinib malate (XL184) induces apoptosis.

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Description

Cabozantinib malate (XL184) is the malate of Cabozantinib, a potent VEGFR2inhibitor with IC50of 0.035 nM and also inhibits c-Met, Ret (c-Ret), Kit (c-Kit), Flt-1/3/4, Tie2, and AXL with IC50of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively. Cabozantinib malate (XL184) induces apoptosis.