Limba
Romanian
Romanian
English|
BX-795 is a potent and specific PDK1inhibitor with IC50of 6 nM, 140- and 1600-fold more selective for PDK1 than PKA and PKC in cell-free assays, respectively. Meanwhile, in comparison to GSK3β more than 100-fold selectivity observed for PDK1. BX-795 modulates autophagyvia inhibiting ULK1. BX-795 also is a potent TBK1inhibitor that blocks both TBK1 and IKKε with IC 50 values of 6 nM and 41 nM, respectively.
| Price | 1.278,00 RON (preturile sunt fara TVA) |
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| Description |
BX-795 is a potent and specific PDK1inhibitor with IC50of 6 nM, 140- and 1600-fold more selective for PDK1 than PKA and PKC in cell-free assays, respectively. Meanwhile, in comparison to GSK3β more than 100-fold selectivity observed for PDK1. BX-795 modulates autophagyvia inhibiting ULK1. BX-795 also is a potent TBK1inhibitor that blocks both TBK1 and IKKε with IC 50 values of 6 nM and 41 nM, respectively. |
