BRD3308, 1g

BRD3308, 1g

BRD3308, 25mg

BRD3308, 25mg

BRD3308, 5mg

1.200,32 RON
SKU
SKM_S8962_5mg

BRD3308 is a potant and highly selective inhibitor of HDAC3with IC50 of 54 nM, 1.26 μM and 1.34 μM for HDAC3, HDAC1 and HDAC2, respectively. BRD3308 activates HIV-1 transcription. BRD3308 suppresses pancreatic β-cell apoptosis induced by inflammatory cytokines (glucolipotoxic stress) and increases functional insulin release.

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Description

BRD3308 is a potant and highly selective inhibitor of HDAC3with IC50 of 54 nM, 1.26 μM and 1.34 μM for HDAC3, HDAC1 and HDAC2, respectively. BRD3308 activates HIV-1 transcription. BRD3308 suppresses pancreatic β-cell apoptosis induced by inflammatory cytokines (glucolipotoxic stress) and increases functional insulin release.