Bortezomib, 10mM/1mL

Bortezomib, 10mM/1mL

Bosutinib, 10mg

Bosutinib, 10mg

Bosutinib, 1g

9.688,98 RON
SKU
SKM_S1014_1g

Bosutinib is a novel, dual Src/Ablinhibitor with IC50of 1.2 nM and 1 nM in cell-free assays, respectively. Bosutinib also effectively decreases the activity of PI3K/AKT/mTOR, MAPK/ERKand JAK/STAT3signaling pathways by blocking the phosphorylation levels of p-ERK, p-S6, and p-STAT3. Bosutinib promotes autophagy.

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Description

Bosutinib is a novel, dual Src/Ablinhibitor with IC50of 1.2 nM and 1 nM in cell-free assays, respectively. Bosutinib also effectively decreases the activity of PI3K/AKT/mTOR, MAPK/ERKand JAK/STAT3signaling pathways by blocking the phosphorylation levels of p-ERK, p-S6, and p-STAT3. Bosutinib promotes autophagy.