Limba
Romanian
Romanian
English|
BO-264 is a potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3)with IC50 of 188 nM and Kd of 1.5 nM. BO-264 specifically blocks the function of FGFR3-TACC3fusion protein. BO-264 induces SAC-dependent mitotic arrest, apoptosisand DNA damage with antitumor activities.
| Price | 992,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
BO-264 is a potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3)with IC50 of 188 nM and Kd of 1.5 nM. BO-264 specifically blocks the function of FGFR3-TACC3fusion protein. BO-264 induces SAC-dependent mitotic arrest, apoptosisand DNA damage with antitumor activities. |
