YM-58483 (BTP2), 10mM/1mL

YM-58483 (BTP2), 10mM/1mL

BMS-986142, 5mg

BMS-986142, 5mg

BMS-986142, 1mg

1.180,48 RON
SKU
SKM_S8381_1mg

BMS-986142 is a potent and highly selective reversible small molecule inhibitor of BTK with an IC50 of 0.5 nM. In a panel of 384 kinases, only five kinases were inhibited by BMS-986142 with less than 100-fold selectivity for BTK (TEC, ITK, BLK, TXK and BMX).

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Description

BMS-986142 is a potent and highly selective reversible small molecule inhibitor of BTK with an IC50 of 0.5 nM. In a panel of 384 kinases, only five kinases were inhibited by BMS-986142 with less than 100-fold selectivity for BTK (TEC, ITK, BLK, TXK and BMX).