BML-277 (Chk2 Inhibitor II), 100mg

BML-277 (Chk2 Inhibitor II), 100mg

BML-277 (Chk2 Inhibitor II), 10mM/1mL

BML-277 (Chk2 Inhibitor II), 10mM/1mL

BML-277 (Chk2 Inhibitor II), 1g

12.909,12 RON
SKU
SKM_S8632_1g

BML-277 (Chk2 Inhibitor II) is an ATP-competitive inhibitor of Chk2with IC50 of 15 nM. It is 1000-fold more selective toward Chk2 serine/threonine kinase than for Chk1 and Cdk1/B kinases. Chk2 Inhibitor II (BML-277) dose dependently protects human CD4(+) and CD8(+) T-cells from apoptosisdue to ionizing radiation.

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Description

BML-277 (Chk2 Inhibitor II) is an ATP-competitive inhibitor of Chk2with IC50 of 15 nM. It is 1000-fold more selective toward Chk2 serine/threonine kinase than for Chk1 and Cdk1/B kinases. Chk2 Inhibitor II (BML-277) dose dependently protects human CD4(+) and CD8(+) T-cells from apoptosisdue to ionizing radiation.