Bisindolylmaleimide IX (Ro 31-8220) Mesylate, 10mM/1mL

Bisindolylmaleimide IX (Ro 31-8220) Mesylate, 10mM/1mL

Bisindolylmaleimide I (GF109203X), 10mg

Bisindolylmaleimide I (GF109203X), 10mg

Bisindolylmaleimide I (GF109203X), 1mg

1.180,48 RON
SKU
SKM_S7208_1mg

Bisindolylmaleimide I (GF109203X, GO 6850) is a potent PKCinhibitor with IC50of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ in cell-free assays, respectively, showing more than 3000-fold selectivity for PKC as compared to EGFR, PDGFR and insulin receptor.

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Description

Bisindolylmaleimide I (GF109203X, GO 6850) is a potent PKCinhibitor with IC50of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ in cell-free assays, respectively, showing more than 3000-fold selectivity for PKC as compared to EGFR, PDGFR and insulin receptor.