S1406S,  RNA Cap Struc Analog [G(5')ppp(5')A] - 25 A260 units

S1406S, RNA Cap Struc Analog [G(5')ppp(5')A] - 25 A260 units

S1407S,  RNA Cap Struc Analog [G(5')ppp(5')G] - 25 A260 units

S1407S, RNA Cap Struc Analog [G(5')ppp(5')G] - 25 A260 units

S1407L, RNA Cap Struc Analog [G(5')ppp(5')G] - 125 A260 units

3.717,56 RON

Co-transcriptional capping with T7 RNA polymerase from the phi2.5 promoter that contains an A at the transcription initiation site.

SKU
NEB_S1407L

Co-transcriptional capping with T7 RNA polymerase from the phi2.5 promoter that contains an A at the transcription initiation site. The 5´terminal m7G cap present on most eukaryotic mRNAs promotes translation in vitro at the initiation level. For most RNAs, elimination of the cap structure causes a loss of stability, especially against exonuclease degradation, and a decrease in the formation of the initiation complex of mRNAs for protein synthesis. Certain prokaryotic mRNAs containing a 5´ terminal cap structure are translated as efficiently as or more efficiently than eukaryotic mRNAs in a eukaryotic cell-free protein synthesizing system. Also a cap requirement has been observed for splicing eukaryotic substrate RNAs.

Sequence
G(5')ppp(5')G

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Description

Co-transcriptional capping with T7 RNA polymerase from the phi2.5 promoter that contains an A at the transcription initiation site. The 5´terminal m7G cap present on most eukaryotic mRNAs promotes translation in vitro at the initiation level. For most RNAs, elimination of the cap structure causes a loss of stability, especially against exonuclease degradation, and a decrease in the formation of the initiation complex of mRNAs for protein synthesis. Certain prokaryotic mRNAs containing a 5´ terminal cap structure are translated as efficiently as or more efficiently than eukaryotic mRNAs in a eukaryotic cell-free protein synthesizing system. Also a cap requirement has been observed for splicing eukaryotic substrate RNAs.

Sequence
G(5')ppp(5')G