P0773S, EGCase I - 150 mU

Endoglycoceramidase I (EGCase I) catalyzes the hydrolysis of the β-glycosidic linkage between oligosaccharides and ceramides in various glycosphingolipids. The enzyme leaves the oligosaccharide and ceramide intact, keeping them suitable for further analysis. The enzyme efficiently releases oligosaccharides from ganglio- and globo-type glycosphingolipids, certain type of cerebrosides (glucosylcerebrosides), and exhibits low activity towards galactocerebrosides (See Reference 1, FAQ #3). EGCase I does not hydrolyze sulfatides nor psychosine.

Product Source

EGCase I is isolated from a strain of E. coli, which contains the cloned EGCase I gene from Rhodococcus triatomea.