M0226M, SssI (CpG) Methyltransferase, conc. - 500 units

The CpG Methyltransferase, M.SssI, methylates all cytosine residues (C5) within the double-stranded dinucleotide recognition sequence 5'...CG...3'.

May be useful for epigenetics - studying cytosine methylation in higher eukaryotes as its specificity mimics the pattern of modification found in their genomes.
Blocking restriction enzyme cleavage
Studying of CpG methylation-dependent gene expression
Probing sequence-specific contacts within the major groove of DNA
Altering the physical properties of DNA
Uniform (3H)-labeling of DNA
Decreasing the number of sites cut by restriction endonucleases, yielding an apparent increase in specificity

Product Source
The CpG Methyltransferase(M.SssI) is isolated from a strain of E. coli which contains the Methyltransferase gene from Spiroplasma sp. strain MQ1.