RKI-1447, 10mM/1mL

RKI-1447, 10mM/1mL

BIO, 50mg

BIO, 50mg

BIO, 10mg

1.180,48 RON
SKU
SKM_S7198_10mg

BIO (GSK-3 Inhibitor IX, 6-bromoindirubin-3-oxime, 6-Bromoindirubin-3'-oxime, MLS 2052) is a specific inhibitor of GSK-3with IC50of 5 nM for GSK-3α/β in a cell-free assay, shows >16-fold selectivity over CDK5, also a pan-JAKinhibitor with IC50 of 30 nM for Tyk2. BIO induces apoptosisin human melanoma cells.

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Description

BIO (GSK-3 Inhibitor IX, 6-bromoindirubin-3-oxime, 6-Bromoindirubin-3'-oxime, MLS 2052) is a specific inhibitor of GSK-3with IC50of 5 nM for GSK-3α/β in a cell-free assay, shows >16-fold selectivity over CDK5, also a pan-JAKinhibitor with IC50 of 30 nM for Tyk2. BIO induces apoptosisin human melanoma cells.