Limba
Romanian
Romanian
English|
BI-2852 is a potent inhibitor of KRASthat binds with nanomolar affinity to a pocket between switch I and II on RAS. BI-2852 blocks all GEF, GAP, and effector interactions with KRAS, leading to inhibition of downstream signaling and an antiproliferative effect in the low micromolar range in KRAS mutant cells.
| Price | 16.018,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
BI-2852 is a potent inhibitor of KRASthat binds with nanomolar affinity to a pocket between switch I and II on RAS. BI-2852 blocks all GEF, GAP, and effector interactions with KRAS, leading to inhibition of downstream signaling and an antiproliferative effect in the low micromolar range in KRAS mutant cells. |
