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Bemcentinib (R428, BGB324) is an inhibitor of Axlwith IC50of 14 nM, >100-fold selective for Axl versus Abl. Selectivty for Axl is also greater than Mer and Tyro3 (50-to-100- fold more selective) and InsR, EGFR, HER2, and PDGFRβ (100- fold more selective).
| Price | 10.848,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
Bemcentinib (R428, BGB324) is an inhibitor of Axlwith IC50of 14 nM, >100-fold selective for Axl versus Abl. Selectivty for Axl is also greater than Mer and Tyro3 (50-to-100- fold more selective) and InsR, EGFR, HER2, and PDGFRβ (100- fold more selective). |
