BAY-985, 100mg

BAY-985, 100mg

VBIT-12, 5mg

VBIT-12, 5mg

BAY-985, 10mM/1mL

4.544,61 RON
SKU
SKM_S8935_10mM/1mL

BAY-985 is a potent and highly selective TBK1/IKKεinhibitor. BAY-985 shows high potency toward TBK1(IC50 = 2 nM, low ATP assay; 30 nM, high ATP assay) and IKKε(IC50 = 2 nM), as well as high potency in the mechanistic pIRF3 assay (IC50 = 74 nM), and an antiproliferative effect on SK-MEL-2 cells (IC50 = 900 nM).

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Description

BAY-985 is a potent and highly selective TBK1/IKKεinhibitor. BAY-985 shows high potency toward TBK1(IC50 = 2 nM, low ATP assay; 30 nM, high ATP assay) and IKKε(IC50 = 2 nM), as well as high potency in the mechanistic pIRF3 assay (IC50 = 74 nM), and an antiproliferative effect on SK-MEL-2 cells (IC50 = 900 nM).