B102(PARP/HDAC-IN-1), 100mg

B102(PARP/HDAC-IN-1), 100mg

SLF1081851 hydrochloride, 5mg

SLF1081851 hydrochloride, 5mg

B102(PARP/HDAC-IN-1), 1g

19.336,31 RON
SKU
SKM_E1912_1g

B102(PARP/HDAC-IN-1) is a dual inhibitor of PARPand HDAC, with IC50 of 19.01 nM, 2.13 nM, 1.69 μM, > 10 μM for PARP1, PARP2, HDAC1, HDAC6, respectively, in an enzymatic assay. It exhibits anti-proliferative and anti-tumor effects. It also induces DNA damage and apoptosis in vitro.

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Description

B102(PARP/HDAC-IN-1) is a dual inhibitor of PARPand HDAC, with IC50 of 19.01 nM, 2.13 nM, 1.69 μM, > 10 μM for PARP1, PARP2, HDAC1, HDAC6, respectively, in an enzymatic assay. It exhibits anti-proliferative and anti-tumor effects. It also induces DNA damage and apoptosis in vitro.