Avapritinib, 5mg

Avapritinib, 5mg

Avapritinib, 1g

Avapritinib, 1g

Avapritinib, 25mg

5.316,92 RON
SKU
SKM_S8553_25mg

Avapritinib is a small molecule kinase inhibitor that potently inhibits PDGFRα D842Vmutant activity in vitro (IC50 = 0.5 nM) and PDGFRα D842V autophosphorylation in the cellular setting (IC50 = 30 nM); also a potent inhibitor of the analogous Kit (c-Kit)mutation, D816V in Kit (c-Kit) Exon 17 (IC50 = 0.5 nM).

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Price 4.468,00 RON (preturile sunt fara TVA)
Description

Avapritinib is a small molecule kinase inhibitor that potently inhibits PDGFRα D842Vmutant activity in vitro (IC50 = 0.5 nM) and PDGFRα D842V autophosphorylation in the cellular setting (IC50 = 30 nM); also a potent inhibitor of the analogous Kit (c-Kit)mutation, D816V in Kit (c-Kit) Exon 17 (IC50 = 0.5 nM).