Atuveciclib (BAY-1143572), 25mg

Atuveciclib (BAY-1143572), 25mg

PK11000, 10mg

PK11000, 10mg

Atuveciclib (BAY-1143572), 10mM/1mL

2.614,43 RON
SKU
SKM_S8727_10mM/1mL

Atuveciclib (BAY-1143572) is a potent and highly selective PTEFb/CDK9inhibitor with IC50values of 13 nM for CDK9/CycT and the ratio of IC50 values for CDK2/CDK9 is about 100. Outside the CDK family, It inhibits GSK3 kinase with IC50 values of 45 nM and 87 nM for GSK3α and GSK3β respectively.

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Description

Atuveciclib (BAY-1143572) is a potent and highly selective PTEFb/CDK9inhibitor with IC50values of 13 nM for CDK9/CycT and the ratio of IC50 values for CDK2/CDK9 is about 100. Outside the CDK family, It inhibits GSK3 kinase with IC50 values of 45 nM and 87 nM for GSK3α and GSK3β respectively.