Ataluren (PTC124), 10mg

Ataluren (PTC124), 10mg

Ataluren (PTC124), 10mM/1mL

Ataluren (PTC124), 10mM/1mL

Ataluren (PTC124), 1g

11.168,15 RON
SKU
SKM_S6003_1g

Ataluren (PTC124) selectively induces ribosomal read-through of premature but not normal termination codons, with EC50of 0.1 μM in HEK293 cells, may provide treatment for genetic disorders caused by nonsense mutations(e.g. CF caused by CFTR nonsense mutation). Phase 3.

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Description

Ataluren (PTC124) selectively induces ribosomal read-through of premature but not normal termination codons, with EC50of 0.1 μM in HEK293 cells, may provide treatment for genetic disorders caused by nonsense mutations(e.g. CF caused by CFTR nonsense mutation). Phase 3.