BMS309403, 10mM/1mL

BMS309403, 10mM/1mL

APY29, 25mg

APY29, 25mg

APY29, 5mg

1.180,48 RON
SKU
SKM_S6623_5mg

APY29 is a type I kinase inhibitor of IRE1αthat binds to the ATP-binding site on IRE1α and inhibits its autophosphorylation (IC50 = 280 nM) and enhances its RNase function (EC50 = 460 nM).

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Description

APY29 is a type I kinase inhibitor of IRE1αthat binds to the ATP-binding site on IRE1α and inhibits its autophosphorylation (IC50 = 280 nM) and enhances its RNase function (EC50 = 460 nM).