Limba
Romanian
Romanian
English|
Apitolisib (GDC-0980), 5mg
1.331,61 RON
SKU
SKM_S2696_5mg
Apitolisib (GDC-0980, RG7422, GNE 390) is a potent, class I PI3K inhibitor for PI3Kα/β/δ/γwith IC50of 5 nM/27 nM/7 nM/14 nM in cell-free assays, respectively. Also a mTORinhibitor with Kiof 17 nM in a cell-free assay, and highly selective versus other PIKK family kinases. Apitolisib activates autophagyand apoptosissimultaneously in pancreatic cancer cells. Phase 2.
| Price | 1.119,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
Apitolisib (GDC-0980, RG7422, GNE 390) is a potent, class I PI3K inhibitor for PI3Kα/β/δ/γwith IC50of 5 nM/27 nM/7 nM/14 nM in cell-free assays, respectively. Also a mTORinhibitor with Kiof 17 nM in a cell-free assay, and highly selective versus other PIKK family kinases. Apitolisib activates autophagyand apoptosissimultaneously in pancreatic cancer cells. Phase 2. |
