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Romanian
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English|
Apilimod is a potent and orally-available inhibitor of the cytokines interleukin-12 (IL-12)and interleukin-23 (IL-23)with the potential to treat certain autoimmune and inflammatory diseases. Apilimod (STA-5326) inhibits IL-12 with IC50 of 1 nM, 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs, human monocytes and mouse PBMCs, respectively. Apilimod (STA-5326) is also a cell permeable small molecule that specifically inhibits PIKfyvewith IC50 of 14 nM.
| Price | 27.172,00 RON (preturile sunt fara TVA) |
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| Description |
Apilimod is a potent and orally-available inhibitor of the cytokines interleukin-12 (IL-12)and interleukin-23 (IL-23)with the potential to treat certain autoimmune and inflammatory diseases. Apilimod (STA-5326) inhibits IL-12 with IC50 of 1 nM, 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs, human monocytes and mouse PBMCs, respectively. Apilimod (STA-5326) is also a cell permeable small molecule that specifically inhibits PIKfyvewith IC50 of 14 nM. |
