Limba
Romanian
Romanian
English|
Alofanib (RPT835) is a novel selective allosteric inhibitor of FGFR2and has a dramatic inhibitory effect with IC50 <10 nM on FGF2-induced phoshphorylation of FRS2a in KATO III cells. It has no direct effect on FGF2-dependent FGFR1 and FGFR3 phosphorylation levels in either cell lines and no effects on FGF2-FGFR2 binding.
| Price | 992,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
Alofanib (RPT835) is a novel selective allosteric inhibitor of FGFR2and has a dramatic inhibitory effect with IC50 <10 nM on FGF2-induced phoshphorylation of FRS2a in KATO III cells. It has no direct effect on FGF2-dependent FGFR1 and FGFR3 phosphorylation levels in either cell lines and no effects on FGF2-FGFR2 binding. |
