Limba
Romanian
Romanian
English|
AKOS B018304 (C6;NSC 43396) is an arylalkylidene derivative with a polar substitution at the para-position. It functions as an inhibitor of ΔFosBby allosterically inhibiting its binding to DNA. It disrupts ΔFosB binding to TMR-cdk5 with an IC50 value of 10.1 μM and also induces a structural change in ΔFosB that prevents the protein from binding to DNA.
| Price | 2.307,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
AKOS B018304 (C6;NSC 43396) is an arylalkylidene derivative with a polar substitution at the para-position. It functions as an inhibitor of ΔFosBby allosterically inhibiting its binding to DNA. It disrupts ΔFosB binding to TMR-cdk5 with an IC50 value of 10.1 μM and also induces a structural change in ΔFosB that prevents the protein from binding to DNA. |
