Limba
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Agerafenib (CEP-32496) is a highly potent inhibitor of BRAF(V600E/WT)and c-Rafwith Kdof 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret (c-Ret), PDGFRβ and VEGFR2, respectively; insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2. Phase 1/2.
Price | 1.658,00 RON (preturile sunt fara TVA) |
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Description |
Agerafenib (CEP-32496) is a highly potent inhibitor of BRAF(V600E/WT)and c-Rafwith Kdof 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret (c-Ret), PDGFRβ and VEGFR2, respectively; insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2. Phase 1/2. |