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Acalabrutinib (ACP-196), 10mM/1mL
1.501,78 RON
SKU
SKM_S8116_10mM/1mL
Acalabrutinib (ACP-196) is a selective second-generation Bruton's tyrosine kinase (BTK)inhibitor with an IC50 of 3 nM, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. ACP-196 has improved target specificity with 323-, 94-, 19- and 9-fold selectivity over the other TEC kinase family members (ITK, TXK, BMX, and TEC, respectively) and no activity against EGFR.
| Price | 1.262,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
Acalabrutinib (ACP-196) is a selective second-generation Bruton's tyrosine kinase (BTK)inhibitor with an IC50 of 3 nM, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. ACP-196 has improved target specificity with 323-, 94-, 19- and 9-fold selectivity over the other TEC kinase family members (ITK, TXK, BMX, and TEC, respectively) and no activity against EGFR. |
