5' PC Biotin 200 nmol scale, 1 modification020

Biotin-labelled oligonucleotides can be used to link the oligonucleotide to streptavidin-protein conjugates, streptavidin affinity columns, or labelled streptavidin. Attachment of a biotin molecule to the 3’ terminus can also be used to prevent 3’ exonuclease digestion and 3’ extension during amplification reactions

PC Biotin stands for Photocleavable biotin. The spacer between the nucleic acid sequence and the biotin molecule is broken under exposure to a 300 -350 nm wavelength light.