3' Thiophosphate 1000 nmol scale, 1 modification

Thiophosphates (also known as phosphorothioates) are chemical compounds containing one or more sulfur and oxygen atoms linked to a phosphorus atom.
Monothiophosphates have a general chemical formula : [PO3S]3- and are used in oligonucleotides to increase the backbone resistance against nuclease digestion.

These analogs of phosphate with the substitution of a non-bridging oxygen by sulphur can be used in transcription studies, silencing.

Thiophosphates also known as Phosphorothioate bonds possess an increased resistance against nucleases due to the substitution of a non-bridging oxygen by sulphur.