Anti-Endoglin (CD105) mouse monoclonal, 0,1 ml, Species x-Reactivity: human, Applications: IHC

CD105/Endoglin

Cat#: BSH-7631-100, 100ul, BSH-7631-1, 1ml

Alias names: ENG, END, ORW, HHT1, ORW1, CD105, FLJ41744, Optibodies, Optibody

MW:  71kDa

Substrate/Buffer:  TRIS with 0.03% sodium azide, pH7,2

Clonality: Mouse monoclonal antibody

Clone: BS71

Application: IHC-P

S/R: Human

Control tissues: Tonsil and appendix

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as OslerRendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Endoglin is higly expressed especially in vascular tumor endothelia.

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Endoglin – Tonsil Tonsil section has been stained using endoglin optibody (Clone: BS71) with 1:200 dilution. Endoglin stains vascular endothelia with moderate to strong intensity.		Endoglin – Urinary bladder carcinoma Tonsil section has been stained using endoglin optibody (Clone: BS71) with 1:200 dilution. Endoglin stains vascular endothelia with moderate to strong intensity.		Endoglin – Ductal breast adenocarcinoma Ductal breast adenocarcinoma section has been stained with endoglin optibody (Clone: BS71) with 1:200 dilution. Vascular endothelia are strongly stained in intratumoral area.