We offer a wide range of services associated with these types of laboratories: DNA sequencing [PCR amplicons, plasmids, or whole genomes (NextGen sequencing)], comparing the pattern of DNA methylation, genome analysis services (using ILLUMINA platform), interactions between DNA and proteins analysis (chip-seq), mutagenesis, cloning, gene synthesis «in vitro», synthesis of oligonucleotides (primers and probes for PCR & qPCR), peptide synthesis, protein expression and purification services, synthesis and purification of polyclonal antibodies, advisory services and technical assistance to develop research projects requiring kits, reagents, equipment and services proposed (particularly in the areas of GENOMICS, PROTEOMICS, METHYLOMICS).
We offer products and services for the detection and testing endotoxin levels for pharmaceutical companies and manufacturers of injection solutions, medications, supplies or other instruments and medical devices.
One thing that concerned us from the beginning was to only include in our portfolio high quality products and services made by major companies recognized worldwide. This allows us to offer a 100% guarantee on all products and services.
Working with Bio Zyme you are not alone but you have over 1000 specialists from all over the world: technical support of any producer with which we work is just a click away: any question, problem or situation will be reviewed and resolved quickly in a professional manner.
Life Science Oligonucleotides, used for PCR and qPCR are manufactured under ISO 9001 quality standards. Highly modified Oligonucleotides, sophisticated chimeras, siRNA coupled to various peptides, are synthesized every day in our facitilites. Today, more than 35000 customers benefit from a large variety of synthesis scale, more than 300 modifications, an extensive range of purifications and various formats for their Oligonucleotides. We guarantee the following benefits for our exceptional products: sizes from 2 to 225 bases, all chemistries: DNA, RNA, LNA®, 2’O-Me RNA, PNA, more than 300 modifications, from Lab scale to Large scale (nano, micro, milli or gram quantities), from Research to Diagnostic grade. To get rid of bureaucracy and to be able to order 7 days 7, 24 H / 24 primers and probes for PCR and qPCR, we suggest you to open an "nucleotide account", named Oli&GO™ account, which you can configure and order wanted oligonucleotides online, with delivery in 2-6 days in your lab.
Sequencing short DNA fragments ( max 1300 bp, SANGER SEQUENCING).
Complete sequencing of genomes and transciptom analysis (RNA-SEQ) based on Next-Generation Sequencing Technology (NGS), using Illumina (HiSEQ2500 and MiSEQ) and Pacific Biosciences (PaqBio RS II) platforms.
The use of the most modern methods (Next Gen Sequencing, NGS) to investigate methylation (5-mc) and hydroxy methylation (5-hmC) of DNA in one or several genomes in parallel (Genome-wide epigenetic analysis), Chip-SEQ, Small & Regulatory RNAs, RNA-Seq, Mass Spec, Bioinformatics (rapid delivery of fully analyzed results in a format "ready to publish").
Various bioinformatics services: sequences alignment, de novo assembly of new genes, analysis of SNPs and chromosomal rearrangements, annotating genomes, transcriptome analysis, human exom analysis, Chip-seq analysis (Protein - DNA interactions), meta genomes analysis , customized projects, developed through collaboration between you and our experts in bioinformatics. Training in bioinformatics (CLCbio software).
Microbial taxonomic profiling, microbiome sequencing and profiling (to identify all species and determine their relative abundance in a sample), customized bioinformatics analysis (data comparisons and statistical analysis), for human microbiome analysis (mainly from faeces), soil, swabs and any biological samples.
The identification of bacteria and fungi (using validated technique MicroSeq), sequencing the genomes of microorganisms and viruses, testing and identification of mycoplasmas, for the pharmaceutical companies, food industry, agriculture, medical centers and research groups.
Obtaining DNA libraries, cloning using PCR technique, customized cloning, mutagenesis services, customized gene synthesis services.
Analysis of genetic variation (general genotyping), screening of point or multiple mutations (SNP or tandem-repeat numbers (VNTR & STR); identification of cell lines (STR profilling through DNA fingerprinting, in accordance with ISO17025 standard); analysis of polymorphisms of genes involved in human behavior.
Rapid and high quality discovery of DNA profiles from different biological samples.
Customized production of polyclonal antibodies.
Customized synthesis of peptides or peptide collections (peptide libraries), numerous changes, scale synthesis and possible purities.
In vitro synthesis of proteins, using acellular proprietary systems, PUREfrex™, starting from ultrapure components. These systems are capable of generating within a few hours the protein of interest to you (eg: 150 µg DHFR /mL).
Services of marking primary or secondary antibodies, proteins and peptides of different molecules for subsequent use in the immunofluorescence staining, in situ hybridization, flow cytometry and other biological applications.