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Reduced representation bisulfite sequencing (RRBS)

DNA methylation studies with RRBS

  • The latest bisulfite conversion and Illumina sequencing technologies
  • Single nucleotide resolution through CpG methylation analysis
  • Ready-to-publish data

Reduced representation bisulfite sequencing (RRBS) enables genome-scale DNA methylation analysis in any vertebrate species.

The assay benefits from the practical advantages of bisulfite sequencing while avoiding the cost of whole-genome sequencing.

The Diagenode RRBS service makes this technology widely available and provides high coverage (up to 4 million CpGs in human samples).

Multiplexing prior to bisulfite conversion allows processing of 96 samples per experiment, enabling studies of large cohorts.

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